Trypanosomiasis

COMPOSITION :
Each sachet contains :
Diminazene Diaceturate  1.05 g
Phenazone BP                1.31 g

INDICATION :
Trypanosomes and Piroplasms

USE :
Dissolve the content of the sachet into 15 ml of sterile water.

DOSAGE :
15 ml of reconstituted solution for 300 kg b.w. by deep intramuscular injection.

STORAGE CONDITION :
Store below 25⁰C in a dry place. Do not freeze.

WITHDRAWAL PERIOD :

Meat : 21 days
Milk Deliver : 3 days

PACK SIZE :
Sachets of 2.36 gm

COMPOSITION :
Each sachet contains :
Diminazene Diaceturate 10.5 g
Phenazone BP                13.1 g

INDICATION :
Trypanosomes and Piroplasms
USE :
Dissolve the content of the sachet into 150 ml of sterile water.
DOSAGE :
150 ml of reconstituted solution for 3000 kg b.w. by deep intramuscular injection.

STORAGE CONDITION :
Store below 25⁰C in a dry place. Do not freeze.

WITHDRAWAL PERIOD :

Meat : 21 days
Milk Deliver : 3 days

PACK SIZE :
Sachets of 23.6 gm

COMPOSITION:

Each gm granules contains:

Diminazene Diaceturate B.P. (vet)     444.3 mg

Phenazone BP                                     555.3 mg

Vitamin B₁₂ BP                                                0.4 mg

INDICATION –

Cattle, sheep, goats, horses and dogs:

Treatment of protozoan diseases:

·         Trypansomiasis due to Trypanosomacongolense, T. vivax and T. brucei.

·         Pyroplasmosis due to Babesiabovis, B. bigemina, B. oivs, B. motasi, B. caballi, B. equi and B. canis.

WITHDRAWAL PERIOD –

Animals must not be slaughtered and milk should not be used for human consumption during treatment. The withdrawal periods after the last dose / treatment for all meat and milk producing animals are :- 

Meat : 28 days

Milk : 7 days

PACK SIZE –

2.36 gm sachets

COMPOSITION:

Each gm granules contains:

Diminazene Diaceturate B.P. (vet)     444.3 mg

Phenazone BP                                     555.3 mg

Vitamin B₁₂ BP                                                0.4 mg

INDICATION –

Cattle, sheep, goats, horses and dogs:

Treatment of protozoan diseases:

·         Trypansomiasis due to Trypanosomacongolense, T. vivax and T. brucei.

·         Pyroplasmosis due to Babesiabovis, B. bigemina, B. oivs, B. motasi, B. caballi, B. equi and B. canis.

 WITHDRAWAL PERIOD –

Animals must not be slaughtered and milk should not be used for human consumption during treatment. The withdrawal periods after the last dose / treatment for all meat and milk producing animals are :- 

Meat : 28 days

Milk : 7 days

PACK SIZE –

23.6 gm sachets

COMPOSITION :
Each sachet contains :
Isometamidium Chloride Hydrochloride 1 gm.

DESCRIPTION :
Isometamidium is a phenanthridine aromatic amidine with a narrow therapeutic index which has been marketed for over 30 years as both a prophylactic and a therapeutic trypanocidal agent in the field. Isometamidium chloride is used curatively at lower dosage rates, and prophylactically at higher dosage rates.

INDICATION :

ISOMID is indicated for treatment and prevention of trypanosomiasis caused by Trypanosoma spp. in Cattle, Goats, Sheep, Camels, Horses and Dogs. A preventive dosage ensures protection for 2 to 4 months. When clinical cases occur, the whole group should be treated.

DIRECTIONS :
Dissolve 1 gm of powder with 50 ml (2% solution) or 100 ml (1% solution) of sterile water.

DOSE RATES, PRECAUTIONS:
For use in cattle, sheep, goats, camel, horses & buffaloes.

CONTRAINDICATION :

ISOMID should not be administered subcutaneously.

Avoid concurrent administration of other trypanocidal drugs, particularly diminazene aceturate.

Avoid underdosing.

SIDE EFFECTS :
Individual sensitivity to ISOMID is possible.

DOSAGE AND ADMINISTRATION :

For parenteral administration.

Dissolve the content of one sachet of ISOMID (1 g) in 50 ml or 100 ml of sterile water for injection to obtain a 2% (20 mg/ml) or a 1% (10 mg/ml) solution, respectively. Repeated injections are needed at intervals of 10 to 12 weeks or more, depending on the level of fly challenge. Calves, Goats and Sheep : treatment : 0.25 - 0.5 mg/kg by deep IM injection.
prevention: 0.5 - 1 mg/kg by deep IM injection.
Camels : 0.5 - 0.75 mg/kg using a 1% solution by very slow IV injection.
Horses : 0.5 mg/kg by deep IM injection.
Dogs : 1 mg/kg by deep IM injection.
Deep IM injection should occur preferably in the middle third of the neck in large animals. Doses exceeding 10 ml should be injected at multiple injection sites on each side of the neck. Make sure that the syringe is completely empty before retracting it from the IM injection site. Afterwards, to prevent leakage of ISOMID into subcutaneous tissues, firm pressure must be applied on the injection site. Sheep and Goats are injected deep in their thigh muscles.

WITHDRAWAL PERIOD :
Meat : 1 Month
Milk  :  Nil

PACK SIZE :

Sachet of 1 g. 
One sachet is sufficient for the preventive treatment of 8 animals or the curative treatment of 16 animals, weighing 250 kg each