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Intracin Pharmaceuticals Pvt. Ltd.WHO GMP Accredited Company
Intracin Pharmaceuticals Pvt. Ltd.WHO GMP Accredited Company


Equine Products

We are a leading Manufacturer of ambroxol hydrochloride injection, cyanocobalamin injection usp, levocarnitine injection, dichloro acetic acid injection, imidocarb diproplonate aqueous injection solution and detomidine hydrochloride injection from Nadiad, India.

Ambroxol Hydrochloride Injection

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Ambroxol Hydrochloride Injection
Approx. Rs 400 / vial
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ABXOL

Composition :
Each ml contains :
Ambroxol Hydrochloride BP 6 mg
Water For Injection BP Q.S.

Indication :
ABXOL is indicated to aid in the treatment of catarrhal inflammation of bronchi and the upper respiratory tract in horses and dogs.specific indications include :Chest Infections : acute and chronic,bronchopneumonia,catarrhal rhinitis,strangles,post-viral coughUterine infections : pyometron,mucometronOcular Infections : purulent conjuctivities,hypopion
Actions :
ABXOL is a expectorant. Ambroxol is an active metabolite of bromhexine,and acts to reduce the viscosity of tenacious mucus secretions by fragmentation of long mucopolysaccharide chains,resulting in a productive cough which aids expectoration of liquefied mucoid respiratory secretions,and assists in clearing and maintaing patent bronchioles and alveoli,hence reducing dyspnoea.ABXOL enhances the concentrations of chemotherapeutic agents in bronchial secretions to result in a more rapid recovery.

Dosage And Administration :
Horses : 0.3 mg/kg (5ml/100kg)bodyweight twice daily.Dogs : 0.6 mg/kg (1 ml/kg)bodyweight twice daily.Administer ABXOL by Intravenous Injection.
Withdrawal Period :
Horses : 28 Days

Storage :

Store at a temperature not exceeding 250C. Protect from light.
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Cyanocobalamin Injection USP

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Cyanocobalamin Injection USP
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COMIN
Composition :
Each ml contains :
Cyanocobalamin BP        500 mcg
Benzyl alcohol BP          1.5% v/v
Water For Injection BP           Q.S.

Actions :
Vitamin B12 is essential B complex vitamins, vitally involved in many critical metabolic processes related to coenzymes for tissue formation,DNA synthesis, complete utillisation of carbohydrates and proteins fornervous tissue maintainace and energy production, and blood counts.Vitamin B12 acts in synergy in the formulation of DNA, and deficiencies can have serious consequences,both in performance horses with a high tissue turnover rate, and in pregnancy and growth of young foals.Clinically the first sign of deficiency is anaemia.Lack of Vitamin B12 can create anaemias. As the deficiency may be indistinguishable for either of these essential vitamins, they are often grouped in oneproduct for therapeutic and preventive use.Vitamin B12 is an essential B group vitamin which is involved in many metabolic processes as an importantcoenzyme. Its most important role is in the formation of nucleic acids(DNA) from amino acids.Vitamin B12 is vital to the formation of red and white blood cells and haemoglobin, as well as for rapidly dividing cells which include gastrointestinal epitheleal cells,the growing foetus,skin and hair.Vitamin B12 is involved in the formation of the amino acids methionine and glycine,as well as the vitamincholine.Vitamin B12 supplementation is highly recommended during pregnancy, as deficiencies in younggrowing animals are often associated with retardation.Cooking and storage of feeds destroy Vitamin B12 levels.When antibiotics, particularly sulphar drugs,are used forextended periods, the normal synthesis of Vitamin B12 in the gut will be reduced, and the requirement for Vitamin B12 are increased.Supplements of folic acid are repoted to improve antibody respective animals.
Dosage And Administration :
Horses : 5 - 10 mlDogs : 1 - 2 mlAdminister by Intramuscular Injection regularly twice weekly advised by a Veterinary surgeon.

withdrawal Period :
Horses : Nil

Storage :
Store at a controlled room temperature not exceeding 250C. Protect from direct sun light.
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Levocarnitine Injection

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Levocarnitine Injection
Approx. Rs 400 / vial
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I-CARE
Composition :
Each ml contains :
Levocarnitine BP 200mg
Water For Injection BP Q.S.

Indication :
To improve both sprint and endurance performance.

Actions :
* Muscle levels of I-CARE determine the exercise capacity of muscles.* I-CARE forms the essential transport system for use of fats as an energy source.* I-CARE may help delay muscle fatigue and improve endurance.* I-CARE is essential for normal heart function.* Performance horses recover more effeciently when supplemented with I-CARE.I-CARE is an amino acid which helps transport fats into muscle cells. I-CARE is essential in the transport of fats into muscle cells for production. The muscle levels of I-CARE determine the exercise capacity of muscles. By using fats as energy for muscle contractions, the body is sparing glycogen and delaying the accumulation of lactic acid.I-CARE delays muscle fatigue by reducing lactic acid formation, and improves performance and endurance.I-CARE forms an essential part of the transport system which moves fatty acids into the mitachondria(cell furnaces) for energy production. It thus acts as a buffer by inhibiting lactic acid buildup in muscles,helping to delay fatigue and prevent Tying Up.Demand for I-CARE in heavily execising horses is often not met from the diet, as large amounts are consumed during exercise. Supplementing with I-CARE results in improved energy supply, increased use of fatty acids as an energy source,decresed lactate buildup, and a significant increase in maximum work output.

Dosage And Administration :
Horses : 0.3 mg/kg (5ml/100kg)bodyweight twice daily.Dogs : 0.6 mg/kg (1 ml/kg)bodyweight twice daily.Administer ABXOL by Intravenous Injection.
Withdrawal Period :
Meat withholding period [Horses] : Nil

Storage :
Store at a temperature not exceeding 250C. Protect from light.
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Dichloro Acetic Acid Injection

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Dichloro Acetic Acid Injection
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I-CLOR
Composition :
Each ml contains :
Dichloro-acetic acid 120 mcg
Sodium gluconate USP 250 mg
Water For Injection BP Q.S.

Indication :
To help reduce the incidence of Tying Up by reducing the build-up of lactic acid in muscle cells.

Actions :
I-CLOR contains dichloroacetic acid, which is an activator of the enzyme pyruvate dehydrogenase. This enzyme plays a central role in the process of lactic acid production during hard work.Supplementation with dichloroacetic acid (DCA) results in activation of the enzyme pyruvate dehydrogenase, leading to a reduction in the rate of lactic levels results in a reduction in pH which contributes to muscle fatigue and decreased muscle performance.Supplementation with DCA has been shown to reduce lactic acid accumulation during exercise, and produce a significant delay in muscle fatigue.The pathogenesis of Exertional Rhabdomyolysis(”Tying Up”) in horses is related to lactic acidosis during exercise, and associated low muscle pH. Sodium bicarbonate and dimethylglycine (DMG), which mayhelp to reduce lactic acid accumulation during execise, have been used to assist in the prevention of Tying Up in horses. Similarly, DCA (LACTANASE) results in a reduction in the rate of lactate accumulation, and a delay in the onset of muscle fatigue.

Dosage And Administration :
Give 20 - 40 ml by Intravenous Injection(diluted in 1 Litre saline, or administer via catheter).Administer once weekly for 4 weeks then discontinue for 4 weeks before repeating the course.

Withdrawal Period :
Horses : nil

Storage :
Store at a temperature not exceeding 250C. Protect from light.
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Imidocarb Diproplonate Aqueous Injection Solution

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Imidocarb Diproplonate Aqueous Injection Solution
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IMIX
Composition :
Each ml contains :
Imidocarb Dipropionate 120 mg
Benzyl Alcohol B.P. 2.0%w/v
Water For Injection B.P. Q.S.

For the treatment and prevention of Babesiosis and Anaplasmosis

Indication :
IMIX is used for the treatment of babesiosis in Cattle, Sheep, Horses and Dogs and of anaplasmosis in Cattle. IMIX will also treat ehrlichiosis in Dogs. For Subcutaneous or Intramuscular Injection.

Dosage And Administration :
Dose according to body weight :Cattle : 1 ml per 100 kg bodyweight. In treating mixed infections due to Anaplasma and Babesia,administer 2.5 ml per 100 kg bodyweight.Sheep : 0.5 ml per 50 kg bodyweight.Horses : 2 ml per 10 kg bodyweight. (Intramuscular injection is preferrd). In most cases, a single dose will effect a complete cure, but the treatment of B. equi infections in horses may require 2 doses at an interval of 24 hours.Dogs : 0.25 ml per 10 kg bodyweight. In treating mixed infection due to Ehrlichin and Babesia,administer 0.5 ml per 10 kg bodyweight, 2 doses at an interval of 14 days.It is advised to screen the blood after one treatment for presence of the parasite. Repeat treatment if thetest is positive.

Withdrawal Period :
Milk : 7 DaysMeat : 28 Days

Storage :
Store at a temperature not exceeding 250C. Protect from direct light.
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Detomidine Hydrochloride Injection

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Detomidine Hydrochloride Injection
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T-DIN
Composition :
Each ml contains :
Detomidine Hydrochloride BP     10 mg
Water For Injection BP                 Q.S.

Indication :
TDIN can be used in any situation requiring reliable sedation of horses,particularly if analgesia is also required. As a , the dose can be altered to produce reliable variations in depth and duration of sedation.Withhold feed unit the effects of drug wear off. Failure of relief, or very short relief of pain followingadministration is often an indication of the need for surgical intervention in colics.

Dosage And Administration :
TDIN can be given either intravenously or Intramuscularly, as required.The effect is dose-dependent.The following scale can be used as a guide :Depth of sedation Duration(hrs) Dosa(ml/100 kg) dose(mg/kg)
Mild 0.5-1 hr 0.1-0.2 0.01-0.02
Moderate 1.0-2.0 hrs 0.2-0.4 0.02-0.04
Heavy 2.0-6.0 hrs 0.4-0.8 0.04-0.08

Meat Withdrawal Period :
Not to be used in horses that may be slaughtered for human consumption. For anagesia in cases of spasmodic colic,give: 0.2 - 0.4 ml/100kg(0.02-0.04 mg/kg).This table should be considered as a base from which dosage can be modified to effect,according to the depth and duration of analgesia or sedation required.Donot store at low temperatures.Any unused portion should be discarded 3 months after first broaching vial.

Storage :
Store at a temperature not exceeding 250C. Protect from light.
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Thiamine Injection B.P.

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Thiamine Injection B.P.
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THIACIN
Composition :
Each ml contains :
Thiamine hydrochloride BP 125 mg
Water For Injections BP Q.S.

Actions :
THIACIN injection provides the essencial vitamin Thiamine.THIACIN plays an important role in the metabolism of carbohydrates, and energy production for all cells.Thiamine is most important in the breakdown of pyruvic acid, a waste product in hard working muscles, along with lactic acid. In any situation where carbohydrates are the major energy source, or when glucoseis added to the diet, thiamine requirement is increased significantly. Thiamine is essential as part of the coenzyme which is involved in the breakdown of glucose for energy.Thiamine, in conjunction with Vitamin B6(Pyridoxine) is essential in the metabolism of proteins and aminoacids, Thiamine has effects on all tissues. The most sensitive are nerves, stomach and heart.Thiamine can not store in the body, and it is rapidly absorbed from the intestine or blood, as well as from injection sites. Like all B Complex vitamins, Thiamine is water soluble, so it is rapidly absorbed and excreted from the body, and requires regular supplementation, especially in hard working animals whendietary input will probably not be sufficient.Thiamine is found in both meat and cereal products. Small amounts are manufactured in the gut, as long as horses are not under stress.Thiamine in food is destroyed by cooking.High doses of thiamine are reported to help calm nervous or over excitable horses.Clinical signs of thiamine deficiency include fatigue, muscle weakness, loss of appetite and incresedheart rate. (This may be an important factor in endurance horses fed high grain diets). Many of thesesigns can be traced back to increased tissue levels oflactic and pyruvic acids. Never cells are particularly dependant on carbohydrate metabolism, and normal never function is greatly effected by increased levels ofthese acids during hard work.

Dosage And Administration :
Horses : 5-10 mlDogs : 1-2 mlAdminister by Intramuscular Injection regularly twice weekly, or as advised by a Veterinary surgeon.

Withdrawal Period :
Meat : horses : Nil

Storage :
Store at a temperature not exceeding 250C. Protect from light.
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Folic Acid Injection B.P.

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Folic Acid Injection B.P.
Approx. Rs 300 / vial
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I-LIC
Composition :
Each ml contains :
Folic acid BP 15 mg
Water For Injections BP Q.S.

Actions :
Folic Acid is essential B complex vitamins, vitally involved in many critical metabolic processes related to coenzymes for tissue formation,DNA synthesis, complete utillisation of carbohydrates and proteins fornervous tissue maintainace and energy production, and blood counts.Folic Acid acts in synergy in the formulation of DNA, and deficiencies can have serious consequences,both in performance horses with a high tissue turnover rate, and in pregnancy and growth of young foals.Clinically the first sign of deficiency is anaemia.Lack of folic Acid can create anaemias. As the deficiency may be indistinguishable for either of these essential vitamins, they are often grouped in oneproduct for therapeutic and preventive use.Folic Acid is an essential B group vitamin which is involved in many metabolic processes as an importantcoenzyme. Its most important role is in the formation of nucleic acids(DNA) from amino acids.Folic Acid is vital to the formation of red and white blood cells and haemoglobin, as well as for rapidly dividing cells which include gastrointestinal epitheleal cells,the growing foetus,skin and hair.Folic Acid is involved in the formation of the amino acids methionine and glycine,as well as the vitamincholine.Folic Acid supplementation is highly recommended during pregnancy, as deficiencies in younggrowing animals are often associated with retardation.Cooking and storage of feeds destroy Folic Acid levels.When antibiotics, particularly sulphar drugs,are used forextended periods, the normal synthesis of folic acid inthe gut will be reduced, and the requirement for folic acid are increased.Supplements of folic acid are repoted to improve antibody respective animals.
Dosage And Administration :
Horses : 5 - 10 mlDogs : 1 - 2 mlAdminister by Intramuscular Injection regularly twice weekly advised by a Veterinary surgeon.

Withdrawal Period :
Horses : Nil

Storage :
Store at a temperature not exceeding 250C. Protect from light.
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Intracin Pharmaceuticals Pvt. Ltd.WHO GMP Accredited Company
Alfina Ansari (Marketing Manager)
C-1, B-53, G. I. D. C. ,
Nadiad - 387001, Gujarat, India
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